Every item in Guildrun
Items in Guildrun are equipped on one hero and give that hero stats, an effect, or both. A hero carries up to three of them, so every slot is a choice between raw stats and an effect that fits what the rest of the guild is doing.
They come in four rarities, and the shop rolls better ones the deeper into the run you get. Common items cost 5 Shards, rare 15 and epic 25, with the odds shifting toward the rarer end as the run goes on.
Quest items in Guildrun
Twenty six items carry a quest instead of a plain effect. Complete what it asks, like inflicting a set amount of Poison, and the item pays out for the rest of the run.